IgA肾病中医药的实验研究

摘要

IgA肾病是以系膜区IgA沉积为主要特点的一组最常见的特殊免疫类型的原发性肾小球肾炎.IgA肾病的发生、发展与免疫炎性反应、肾脏纤维化、足细胞损伤等有关.中医药治疗IgA肾病的相关机制尚未完全清楚,动物模型的创新及改良为研究IgA肾病相关机制提供了条件.%IgA nephropathy is a special immune type of primary glomerulonephritis,characterized by mesangial IgA deposition.The development of IgA nephropathy is related to immune-inflammatory response,renal fibrosis,podocyte fibrosis and podocyte injury,et al.The mechanism of treatment of IgA nephropathy with traditional Chinese medicine was not clear.However,innovation and improvement of animal model has provided conditions for following research of IgA nephropathy.