自拟振元汤治疗化疗后血小板减少的临床疗效评价

摘要

To observe curative effects of self-made ZhenYuanTang(changed from LiuWei DiHuang Wan) in treating thrombopenia, side effects of chemotherapy of malignancies. Method: 40 patients with platelet in the range of 20×109/L ~75 ×109/'L after chemotherapy were randomized into treatment group administered with ZhenYuanTang and control group given by interleukin-11 on average. The medication was ceased when peripheral platelet rise to S≥100×109/L. Result: Effective rate and total effective rate of treatment group were superior to that of control group with significant difference (P<0.05). The growth speed of platelet was faster than the treatment. Conclusion: Curative effects of TCM in treating thrombopenia after chemotherapy are superior to interleukin-11 without obvious side effect.%目的:观察自拟振元汤(由六味地黄丸化裁而成)治疗恶性肿瘤化疗所致血小板减少的临床疗效.方法:选择化疗后血小板在20×109/L～75×109/L间的患者共40例,其中治疗组(20例)给予振元汤治疗;对照组(20例)给予白介素-11治疗,观察外周血小板升至≥100×109/L时停药.结果:治疗组显效及总有效率优于对照组,并且血小板增长速度快,差异有统计学意义(P＜0.05).结论:中医药治疗化疗后血小板减少的临床疗效优于白介素-11,并且无明显副作用.