Low-dose CT image denoising method based on generative adversarial network

摘要

In order to solve the problems of artifacts and noise in low-dose computed tomography(CT)images in clinical medical diagnosis,an improved image denoising algorithm under the architecture of generative adversarial network(GAN)was proposed.First,a noise model based on style GAN2 was constructed to estimate the real noise distribution,and the noise information similar to the real noise distribution was generated as the experimental noise data set.Then,a network model with encoder-decoder architecture as the core based on GAN idea was constructed,and the network model was trained with the generated noise data set until it reached the optimal value.Finally,the noise and artifacts in low-dose CT images could be removed by inputting low-dose CT images into the denoising network.The experimental results showed that the constructed network model based on GAN architecture improved the utilization rate of noise feature information and the stability of network training,removed image noise and artifacts,and reconstructed image with rich texture and realistic visual effect.