Objective To analyze the skeletal and dental characters among subjects with Class Ⅲ malocclusions and subjects with normal occlusions by using cone-beam computed tomography.Methods 21 subjects with Class Ⅲ malocclusions and 20 subjects with normal occlusions were assessed with cone-beam computed tomography scans.And the CT images were constructed into 3D model by using medical image processing software Dolphin Imaging 11.0.Anatomical landmarks were located and reference planes were established on the 3D model.The measurements were analyzed by SPSS 17.0.Results The extent of maxillofacial deformity including orbitale, anterior nasal spine and menton increased from top to bottom in adults with facial asymmetry.Homogeneity test of variance of menton had statistically significant differences.There was significant difference in asymmetric index of orbitale and anterior nasal spine between ClassⅢ and ClassⅠmalocclusions(P<0.05).Conclusions Based on this study, the asymmetry rates of craniofacial osseous structure tend to worsen from top to bottom, and the discrepant jaw growth resulting in a Class Ⅲ skeletal pattern results in no more skeletal asymmetry than Class Ⅰskeletal patterns.%目的 使用锥体束CT(cone-beam computed tomography,CBCT)三维成像,在三维坐标系中研究安氏Ⅲ类骨性不对称的特征.方法 使用CBCT采集41例成年人患者的颅面部数据,在Dolphin Imaging 11.0软件中建立三维坐标系,对对照组和试验组的骨性结构的标记点的坐标及不对称系数等进行统计分析.结果 眶点、髁突定点、下颌角点的不对称系数呈现由上至下变大的趋势,颏下点的方差齐性检验有统计学差异,而眶点及前鼻嵴点的不对称系数在安氏Ⅰ类与安氏Ⅲ类的统计比较中,发现有显著差异(P<0.05).安氏Ⅲ类患者的下颌骨比上颌骨不对称发生率明显上升.结论 颅面部骨性结构的不对称率呈由上至下逐渐加重的趋势.安氏Ⅲ类患者的颅面部硬组织并没有显示相对于安氏Ⅰ类对照组的不对称发生率上升.
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