光动力疗法对牙周病主要致病菌的杀灭效果的研究进展

摘要

牙周病是口腔中最常见的细菌感染性疾病之一.牙周病以牙周炎为主,牙周炎的治疗方法包括传统的机械疗法、抗生素疗法和近年来比较受到关注的光动力疗法(photodynamic therapy,PDT).光动力抗菌疗法(antimicrobial photodynamic therapy,aPDT)是通过低能量的激光激活光敏剂,杀伤致病菌,对牙周炎进行无创治疗的疗法.该文就光动力疗法的作用机制、特点及对牙周病主要致病菌的杀灭效果做一综述.%Periodontitis is one of the most common bacterial infection diseases in the oral cavity. The treatment of periodontitis in-cludes traditional mechanical therapy, antibiotic therapy and photodynamic therapy(PDT)which has been more concerned in recent years. Antimicrobial photodynamic therapy(aPDT)is a noninvasive therapy for the periodontium by activating photosensitizer with low energy laser,killing pathogenic bacteria. In this paper,the mechanism and characteristics of photodynamic therapy and the efficacy of photodynamic therapy for the main pathogenic bacteria of periodontitis are reviewed.