心肺耐力与代谢综合征的剂量—效应关系研究

摘要

The cross-sectional study was to analyze the dose-response relationship between cardiorespiratory fitness(CRF) and metabolic syndrome(MS) risk factors of 246 adult men aged 40-49.There was dose-response relationship between CRF and MS with the development of CRF,in other words,the higher level CRF,the smaller risk about MS,especially the BMI and DBP.Compared with low CRF,the odd ratios of high CRF decrease significantly(95%CI,0.337-0.873).There is dose-response between CRF and MS,which may benefit from the higher CRF,and CRF will be regard as the evaluation index for predicting MS risk factors.%通过对246名中年健康男性进行心肺耐力测试,分析心肺耐力（CRF）与代谢综合征（MS）相关风险因素之间的剂量—效应关系。结果表明：CRF水平与MS相关风险因素的比例呈剂量—效应关系,即随着CRF水平的提高,MS相关风险因素的比例呈降低趋势;CRF水平与构成MS相关风险因素呈剂量—效应关系,即随着CRF水平的提高,构成MS的相关风险因素呈降低趋势,其中BMI和DBP呈非常显著性差异（P〈0.01）,其余呈显著性差异（P〈0.05）;与低水平CRF比较,高水平CRF组MS风险下降至0.337～0.873。所以,CRF与MS相关风险因素呈剂量—效应关系,高水平CRF有利于改善MS相关风险因素,CRF是预测MS发病率和相关风险因素的重要因素。