通脉软胶囊对犬急性心肌梗死作用的实验研究

摘要

观察通脉软胶囊对犬急性心肌梗死作用的影响.采用冠脉结扎法造成急性心肌梗死模型.通脉软胶囊能明显改善犬急性心肌梗死,明显减轻由心外膜电图所标测的缺血程度(∑-St),明显减少通过N-BT染色所显示的梗塞区,降低血清AST、CPK、LDH活性.通脉软胶囊能明显缩小心肌梗死范围,起到保护心肌的作用.%To study the effects of Tongmai soft capsule in acute myocardial infarction dogs.Dog model with acute myocardial infarction was established by the ligation of coronary arteries.The results showed the Tongmai soft capsule could significantly improve acute myocardial infarction dogs,decrease the extent of myocardial infarction(∑-ST) assignment tested by epicardial electrocardiogram and reduce the infarction area displayed by N-BT staining,reduce serum AST,CPK and LDH activity in myocardial infarction dogs.Tongmai soft capsulecould could signiticantly reduce the myocardial infarction area.It possessed protective effects on myocardial infarction.