秘宝软胶囊中木香总内酯的含量测定

摘要

The current study was aimed to establish a method for the determination of the content of total costuslactone in MiBao soft capsule , which can evaluate the quality of MiBao soft capsules .Method :The content of total costuslactone in soft capsules was detected by UV spec-trophotometry which used dehydrocostuslactone as standard .The content of total costuslactone in the sample has a good linear relationship in the range of 10μg/mL~50μg/mL in terms of dehydrocostuslactone .The regression equation was Y=0.0135X+0.0084(R2=0.9993) and the re-covery rate was 99.18% ,RSD wa 1.68% .The content determination of total costuslactone in MiBao soft capsule by UV spectrophotometry is simple and reliable ,so it can be used as a method of quality control of MiBao soft capsule .%建立秘宝软胶囊中木香总内酯含量测定方法，以评价秘宝软胶囊的质量。以去氢木香内酯为对照品，采用紫外分光光度法测定软胶囊中木香总内酯的含量。样品秘宝软胶囊中木香总内酯含量以去氢木香内酯计在10μg／mL～50μg／mL范围内具有良好线性关系，回归方程为：Y＝0.0135X＋0.0084，R2＝0.9993，平均回收率为99.18％，RSD为1.68％。采用紫外分光光度法测定秘宝软胶囊中木香总内酯的含量，方法简便、可靠，可作为秘宝软胶囊质量控制的方法。