中药有效成分抗溃疡作用机制研究进展

摘要

Peptic ulcer(PU)mainly refers to chronic ulcer in stomach and duodenum ,its incidence rate in natural crowd is as high as 10% .PU is a common and frequently-occurring disease .Drug administration is the main treatment of peptic ulcer .More than 95% patients are surgery-free because of the active drug treatment .As a result of side effects and high recurrence rate ,patients are unable to be in long -time stable conditions .In recent years ,significant progress in experimental investigation in antiulcer effect of Chinese medicine has been made .In this re-view we will discuss and highlight the mechanism of antiulcer effect of traditional Chinese medicine and its effective components .%消化性溃疡（Peptic ulcer ，PU ）主要指发生在胃及十二指肠的慢性溃疡，自然人群中发病率高达10％，是临床上的常见病、多发病。药物治疗是消化道溃疡的主要治疗方法，积极的药物治疗可使95％以上的患者免于手术治疗，但目前临床所用药物存在不同程度的毒副作用，而且复发率较高。近年来，中药有效成分的抗溃疡作用实验研究取得了显著进展，本文对此做一简单回顾，对中药抗溃疡作用的机制做一初步综述。