老年高血压病患者血压变异性与颈动脉内膜中层厚度的相关性

摘要

目的 以老年高血压病患者为研究对象,探讨颈动脉内膜中层厚度与血压变异性的相关性.方法 将102例老年高血压患者分为IMT正常组(n=49)和IMT异常组(n=53),测定患者IMT和血压变异性,之后分析两者之间的相关性.结果老年高血压病患者IMT除与年龄、病程、BMI、TC、TG、HDL-C等指标相关外,24hSBPSD 、24hSBPCV、dSBPSD 、dSBPCV、nSBPSD、nSBPCV为IMT的独立危险因素.结论 对于老年高血压病患者,在控制血压,干预BMI、TC、TG、HDL-C传统危险因素同时,应重视降低其血压变异性,从而降低靶器官损害和心血管事件.%Objective To investigate into the correlation between IMT and BPV in elderly patients with hypertension.Methods 102 eases of elderly hypertension were divided into IMT normal group(n =49) and IMT abnormal group(n =53),measuring IMT and BPV in patients respectively.Then making an analysis of the relationship between them.Results In addition to age,course of disease,BMI,TC,TG,HDL-C,there are other independent risk factors,which include 24hSBPSD,24hSBPCV,dSBPSD,dSBPCV,nSBPSD,nSBPCV,connected with IMT in elderly hypertensive patients.Conclusion For elderly hypertensive patients,besides controlling the blood pressure and intervening some traditional risk factors like BMI,TC,TG,HDL-C,attention also should be paid to reduce the variability of blood pressure,thereby reducing the target organ damage and cardiovascular events.