58例酒精所致精神障碍MRI表现的回顾性研究

摘要

目的 探讨酒精所致精神障碍MRI表现,并评价颅脑MRI检查在酒精所致精神障碍诊断中的价值.方法 搜集本院临床确认58例酒精所致精神障碍患者的临床及影像学资料.结果 58例患者均有长期嗜酒史,酒精所致精神障碍在临床上主要表现为不同程度的精神及意识障碍.MRI表现有多种表现形式,分别为胼胝体变性11例(18.97％)、韦尼克(Wernicke)脑病2例(3.45％)、广泛皮层性脑萎缩33例,其中合并脑室扩大28例(53.45％)、小脑变性2例(3.45％)、脑白质脱髓鞘10例(17.2％),以上MR改变合并双侧基底节区、半卵圆中心多发或单发腔隙性脑梗死灶12例(20.69％).结论 酒精所致精神障碍在影像上有多种不同的表现形式,主要表现为广泛皮层性脑萎缩合并脑室扩大;胼胝体变性为MRI重要表现,MRI检查有助于临床诊断及预后疗效观察.%Objective To investigate MRI characteristics of alcohol-induced psychiatric disorder and to evaluate the value of brain MRI in the diagnosis of psychiatric disorder caused by alcohol.Methods The clinical manifestations and images of 58 cases with alcohol-induced psychiatric disorder were collected and analyzed.Results 58 patients have long-term alcohol abuse and alcohol-induced psychiatric disorder with the major clinical manifestations of varying degrees of mental disturbance of coneciousness.MRI findings manifested in many forms,respectively,11 cases (18.97％) with degeneration of corpus callosum,2 cases (3.45％) with Wernicke encephalopathy,33 cases with extensive cortical brain atrophy,combined with ventricular dilatation in 28 cases (53.45％) and cerebella degeneration in 2 cases (3.45％) and white matter demyelination in 10 patients (17.2％),12 cases (20.69％) with multiple or single lacunar lesion in bilateral basal ganglia and centrum semiovale.Conclusion Alcohol-induced psychiatric disorder may have a variety of different forms in the MR image.Extensive cortical cerebral atrophy with enlarged ventricles is the main show and corpus callosum degeneration is very important in MRI image.MRI has a high diagnostic value in alcohol-induced psychiatric disorder and observation of curative efficacy.