精神分裂症患者入院时合并血糖异常及相关因素分析

摘要

目的 探讨精神分裂症患者入院时血糖异常的发生状况及影响因素.方法 回顾2014年1月至2016年6月入院时的2992例精神分裂症患者的空腹血糖浓度情况,并分析其影响因素.结果 2992例入院患者中并发血糖异常者539例,占入院总数的18.0%.其中出现低血糖者219例,占7.3%;出现高血糖者320例,占10.7%.二元Logistic回归分析结果显示,民族、年龄是发生低血糖的独立影响因素,文化程度、年龄、是否使用抗精神病药物、体质指数是发生高血糖的独立影响因素.结论 精神分裂症患者入院时可能合并一定程度的血糖异常症状,对入院的高危患者应加强血糖检测和观察,及时纠正血糖浓度异常,指导合理膳食,并注意用药安全,最大程度降低血糖异常的发生率.%Objective To investigate the incidence and influencing factors of blood glucose abnormality in first-hospitalizedschizophreniapatients.Methods The fasting blood glucose levels of 2992 patients with schizophrenia from January 2014 to June 2016 were reviewed and their influencing factors were analyzed.Results Among the 2992 patients admitted to hospital,539 patients had abnormal glucose,accounting for 18.0%.Among them,219 cases of hypoglycemia,accounting for 7.3%;320 cases of hyperglycemia,accounting for 10.7%.Binarylogistic regression analysis showed that ethnicity and age were independent influencing factors of hypoglycemia.The educational level,age,the use of antipsychotic drugs and BMI were the independent influencing factors of hyperglycemia.Conclusion First-hospitalized schizophrenia patients may have a certain degree of abnormal symptoms of bloodglucose,blood glucose testing and observationshould be strengthenedon high risk patients admitted to hospital.Timely correction of abnormal blood glucose levels,correct guide of reasonable diet and drug safety all should be paid attention to so as to achieve the maximum reduction in abnormal blood glucose incidence rate.