METHOD OF DETERMINING THE NECESSITY OF USING PSYCHO PHARMACOTHERAPY AMONG THE PATIENTS WITH DISORDERS OF AUTIST SPECTRUM AT THE MOMENT OF THEIR EXAMINATION

摘要

FIELD: medicine.;SUBSTANCE: invention refers to medicine, namely to psychiatry, and can be used in order to assess the need for psychopharmacotherapy of the patient with autism spectrum disorder (ASD). Method of the invention includes clinical examination of patients, determination of the nosological affiliation of the disease according to ICD-10 and DSM-5 and additionally the neurophysiological examination by means of determining the features of the bioelectrical activity of the patient's brain during electroencephalography, mainly within the range of beta and theta rhythms, and immunological examination of patients by means of determining the enzymatic activity of leukocyte elastase (LE) in the serum of peripheral blood, functional activity of the α1-proteinase inhibitor (α1-PI) and the level of autoantibodies (aAB) to neurospecific antigens – S-100b and to the main myelin protein (MMP). Psycho pharmacotherapy is prescribed to the patient based on the results of clinical examination at the significant excess of the additional studies indicators over the similar ones among healthy children of the corresponding age.;EFFECT: use of the invention allows to evaluate the activity of the current pathological process in the brain of patients with ASD at the time of examination and to determine the need for the drug therapy at the particular stage of the disease course.;1 cl, 2 ex, 2 tbl