Background:The DNA-repair enzyme Artemis is essential for rearrangement of T-and B-cell receptors.Mutations in DCLRE1C,which encodes Artemis,cause Artemis-deficient severe combined immunodeficiency(ART-SCID),which is poorly responsive to allogeneic hematopoietic-cell transplantation.
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机译:3-(OMEGA-(3,5-DI-T-BUTYL-4-HYDROXYPHENYL)Alkanoyl)Pyroles,Deooxyanalogues and Therapyical Use Useof 3-(OMEGA-(3,5-DI-T-BUTYL-4-HYDROXYPHEENYL)Alkanoyl)Pyroles,Deooxy Analogogues and Therapyical Use的使用