Objective: To evaluate the association of liver enzyme levels with serum IL-22 levels. Method: Four hundred and fifty four physical examination subjects were enrolled in Huashan Hospital, and completed a comprehensive examination including IL-22 by ELISA method and the relationship between IL-22 levels and liver enzymes was analyzed by Spearman rank correlation. Result: IL-22 levels were significantly negatively correlated with alanine aminotransferase(ALT), aspartate aminotransferase(AST) and gamma-glutamyl transpeptidase (GGT) (correlation coefficients were -0.122, -0.123 and-0.127, Pvalues were 0.020, 0.019 and 0.015). Conclusion: These results suggested that IL-22 might be associated with liver diseases.% 目的：初步探讨血肝酶水平与血清 IL-22水平的相关情况.方法：对象为华山医院体检者454名,进行全面检查,采用 ELISA 方法检测 IL-22水平,采用 Spearman 等级分析 IL-22水平和肝酶的关系.结果：IL-22水平与谷丙转氨酶、谷草转氨酶及γ-谷氨酰转肽酶明显相关(相关系数分别为-0.122,-0.123及-0.127,P 值分别为0.020,0.019及0.015).结论：血清 IL-22水平与血肝酶水平显著负相关,提示 IL-22可能与肝脏疾病相关.
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