血乳酸联合血糖监测在产后新生儿窒息诊断中的应用

摘要

目的：探讨血乳酸联合血糖监测在产后新生儿窒息诊断中的应用价值。方法：选取2013年2月-2014年3月在我院出生的80例发生窒息的新生儿为观察组，并选取同期健康新生儿30例作为对照组。统计分析两组血乳酸和血糖水平与新生儿窒息的关系并进行产后新生儿窒息发生的危险因素的多因素分析。结果：观察组血乳酸和血糖水平分别为（5.86±2.18）mmol/L和（5.15±2.26）mmol/L，显著高于对照组的（2.81±0.49）mmol/L和（2.74±0.62）mmol/L，差异有统计学意义（P<0.05）。Pearson相关性分析结果显示，血乳酸和血糖水平均与新生儿窒息呈负相关（P<0.05）。logistic多元回归分析结果显示产后新生儿窒息发生的危险因素有高血乳酸、血糖、间接胆红素和血压等。结论：血乳酸联合血糖监测可能成为产后新生儿窒息的重要预测指标，可用于产后新生儿窒息的辅助诊断。%Objective:To investigate the role of the monitoring of blood lactic acid and blood sugar levels in the diagnosis of postpartum neonatal asphyxia. Methods:Eighty newborns with asphyxia in our hospital from February, 2013 to March, 2014 were selected as an observation group and meanwhile 30 cases healthy newborns as a control group. Blood lactate and blood sugar levels in two groups were compared. The relationship between postpartum neonatal asphyxia and both blood lactate and blood sugar levels and risk factors of postpartum neonatal asphyxia were analyzed. Results:Blood lactate and blood sugar levels in the observation group were (5.86±2.18) mmol/L and (5.15±2.26) mmol/L, which were signiifcantly higher than the (2.81±0.49) mmol/L and (2.74±0.62) mmol/L in the control group (P<0.05). The results of Pearson correlation analysis showed that both blood lactate and blood sugar levels were negatively correlated with postpartum neonatal asphyxia (P<0.05). The results of Logistic multivariate regression analysis showed that the risk factors resulting in postpartum newborns asphyxia were ascribed to the high levels of blood lactic acid, blood sugar and indirect bilirubin and blood pressure, etc. Conclusion:The levels of both blood lactic acid and blood sugar may be as an important predictors for postpartum neonatal asphyxia, which can be used for the auxiliary diagnosis of postpartum neonatal asphyxia.