门静脉高压症小动物模型的构建及研究进展

摘要

Portal hypertension (PHT) is the most common and fatal complication of cirrhosis. Animal model is the theoretical basis in PHT research. This paper reviews the common methods used in the establishment of PHT small animal models, as well as their characteristics and research progress. The appropriate animal models can be selected according to different purposes of study.%门静脉高压症是肝硬化最常见且致命的并发症，建立动物模型是研究门静脉高压症的理论基础。本文综述门静脉高压症小动物模型的构建方法及各种模型的特点和研究进展，以在研究中可根据不同目的选用恰当的动物模型。