针刺干预代谢综合征脂代谢功能紊乱的临床观察

摘要

目的：观察针刺背俞穴对代谢综合征(MS)脂代谢紊乱的干预效果,以期为临床调节MS提供一种安全有效的非药物治疗方法。方法依纳入标准选择76例MS患者,并将其随机分为对照组39例和治疗组37例,对照组采取常规药物治疗,治疗组在常规药物治疗基础上加用针刺疗法。治疗40 d后比较两组体重指数(BMI)、血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL-C)、高密度脂蛋白(HDL-C)等指标的变化。结果对照组治疗前后 TC、TG、LDL-C 比较差异有统计学意义(P＜0.05),对照组治疗前后体重指数和高密度脂蛋白比较差异无统计学意义(P＞0.05)；治疗组治疗前后BMI、TC、TG、LDL-C、HDL-C比较差异均有统计学意义(P＜0.05,P＜0.01)；两组治疗后BMI、TC、LDL-C、HDL-C比较差异有统计学意义(P＜0.01)。结论针刺背俞穴干预MS,可显著降低TG、TC、LDL-C水平,改善HDL-C水平,提示针刺干预具有调节MS脂代谢紊乱的作用。%ObjectiveTo observe the efficacy of acupuncture at Back-Shu points in treating lipid metabolism dysfunction due to metabolic syndrome (MS), for providing a safe and effective non-drug treatment for MS.MethodSeventy-six eligible MS patients were randomized into a control group of 39 cases and a treatment group of 37 cases. The control group was intervenedby regular medication, while the treatment group was additionally intervened by acupuncture. Forty days later, the changes of the Body Mass Index (BMI), total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), and high density lipoprotein cholesterol (HDL-C) were observed.ResultIn the control group, TC, TG, and LDL-C levels were changed significantly after intervention (P<0.05), while the BMI and HDL-C were insignificantly changed (P>0.05); in the treatment group, BMI, TC, TG, LDL-C, and HDL-C were significantly changed after intervention (P<0.05,P<0.01); after intervention, there were significant differences in comparing BMI, TC, LDL-C, and HDL-C between the two groups (P<0.01).ConclusionAcupuncture at Back-Shu points can markedly down-regulate the TG, TC, LDL-C levels and enhance the HDL-C level in MS, indicating that acupuncture can regulate the lipid metabolism dysfunction in MS.