树突状细胞在天灸发泡免疫调节中的作用探讨

摘要

As a classical external treatment of traditional Chinese medicine, blistering moxibustion has significant curative effect on asthma, rheumatoid arthritis and other immune disorders, which suggests that it has certain immunoregulation effect. When stimulated, skin immune system evokes innate immune or acquired immune systems, including dendritic cells (DC), a type of crucial cell related to acquired immunity. From the classification and function of DC, especially the differentiation, migration and maturation of DC in local skin after blistering moxibustion. This article was to discuss the possible ways of immunoregulation of DC in local skin after blistering moxibustion, so as to provide reference for the study on immunoregulatory mechanism of blistering moxibustion.%天灸发泡作为中医经典的外治法,对哮喘、类风湿关节炎等免疫紊乱疾病具有较满意的疗效,也反映了该疗法具有一定的免疫调节效应.皮肤免疫系统在皮肤受到刺激时能激活人体固有免疫或获得性免疫,其中树突状细胞(dendritic cell,DC)是获得性免疫相关的主要细胞.该文从DC的分类和作用,特别是天灸发泡后局部皮肤DC的分化、迁移和成熟等角度,探讨天灸发泡后局部皮肤中DC发挥免疫调节作用的可能作用途径,为天灸发泡局部皮肤免疫调节机制研究提供参考.