艾灸章门穴治疗溃疡性结肠炎疗效观察

摘要

目的 观察艾灸章门穴治疗溃疡性结肠炎(ulcerative colitis,UC)的临床疗效.方法 将符合纳入标准的UC患者随机分为艾灸组30例、对照组30例.艾灸组每日口服美沙拉嗪肠溶片,同时隔日艾灸章门穴1次,每次30 min;对照组每日口服美沙拉嗪肠溶片.两组疗程均为8星期,分别于治疗前、治疗第4星期、治疗第8星期进行症状评分及心理状态(SAS、SDS)评分.结果 与治疗前相比,两组总体症状积分在治疗第4星期、治疗第8星期显著降低(P<0.05);与对照组比较,艾灸组总体症状积分在治疗第8星期显著低于对照组(P<0.05).两组治疗第4星期、治疗第8星期SAS和SDS评分均明显降低,与治疗前比较差异有统计学意义(P<0.05).结论 艾灸章门穴能有效改善UC患者临床症状和心理状态.%Objective To observe the clinical efficacy of moxibustion at Zhangmen (LR13) in treating ulcerative colitis (UC).Method The eligible UC patients were randomized into a moxibustion group of 30 cases and a control group of 30 cases. The moxibustion group received daily oral administration of Mesalazin enteric-coated tablets and 30-min moxibustion at Zhangmen once every other day; the control group was intervened by oral administration of Mesalazin enteric-coated tablets per day. The treatment duration was 8 weeks in both groups. The symptoms and mental state (Self-rating Anxiety Scale, SAS; Self-rating Depression Scale, SDS) were evaluated before the treatment, and respectively after 4-week and 8-week treatments.Result The total symptoms scores after 4-week and 8-week treatments were significantly lower than those before the treatment in both groups (P<0.05); after 8-week treatment, the moxibustion group was significantly lower than the control group in comparing the total symptoms score (P<0.05). The SAS and SDS scores after 4-week and 8-week treatments were significantly lower than those before the treatment in both groups (P<0.05).Conclusion Moxibustion at Zhangmen can effectively improve the symptoms and mental state of UC patients.