Objective To assess the clinical efficacy and safety of fire needling therapy for vitiligo. Method A self-control study was carried out. Fifty-six vitiligo patients with 124 skin lesions were allocated by long-axis random to two groups. The treatment group received fire needling therapy weekly for 12 times or until cure and the control group, no treatment as a blank control. The clinical efficacy and safety were assessed after the completion of treatment. Result The total efficacy rate of local fire needling therapy for vitiligo skin lesions was 79.8% and there was a statistically significant difference as compared with the control group (P<0.05). The therapeutic effect was better in patients with faciocervical skin lesions or short course of disease. The therapeutic effect increased with an increase in the course of treatment at the early stage of treatment but did not significantly increase after 8 weeks of treatment. Main adverse reactions were mild pain and skin infection. Conclusion Local fire needling has a definite therapeutic effect on vitiligo with high safety.%目的 评价火针疗法治疗白癜风的临床疗效和安全性.方法 采用自身对照研究方法,将56例白癜风患者124片皮损经长轴随机分为两组,治疗组予火针疗法治疗,每星期1次,连续12次,或至痊愈结束治疗;对照组为空白对照.治疗结束后评价临床疗效和安全性.结果 局部火针治疗白癜风皮损的总有效率为79.8%,与对照组比较差异具有统计学意义(P<0.05).面颈部、病程短患者疗效较好,治疗早期疗效随疗程增加而增加,但8星期后增加不明显.不良反应主要为轻度疼痛感及皮肤感染.结论 局部火针治疗白癜风疗效确切,安全性高.
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