胎儿心脏横纹肌瘤尸检病例分析

摘要

Objective To explore the morphological features, diagnosis and differential diagnosis of the fetal cardiac rhabdomyomas. Methods Four cases of fetal cardiac rhabdomyomas by autopsy were reperted. The tissue sections were stained with HE, immunohistochemistry and PAS. Results Fetal cardiac rhabdomyomas was single or multiple neoplasm with clear margin. Histologically, the "spider cells" were typical. The tumor cells expressed myoglobin and desmin. PAS result was positive. Conclusion Fetal cardiac rhabdomyomas is the most common cardiac tumor in fetus, which can be single or multiple.%目的 探讨胎儿心脏横纹肌瘤的病理形态特点、诊断及鉴别诊断等.方法 报告中国医科大学附属盛京医院的4例胎儿心脏横纹肌瘤尸检病例.标本采用HE染色,并行免疫组化及糖原染色.结果 胎儿心脏横纹肌瘤为单发或多发肿物,界清;镜下可见典型的“蜘蛛细胞”;免疫组化染色示瘤细胞肌源性标记阳性,细胞增殖活性( Ki-67)阴性.结论 心脏横纹肌瘤是胎儿最常见的心脏肿瘤,可单发或多发.