Objective: To explore the clinicopathologic features, Siewert classification of adenocarcinoma of the esophagogastric junction. Methods : The clinical recards of 216 cases of adenocarcinoma of the esophagogastric junction (AEJ) were reviewed. Clinicopathologic and survival characteristics were analyzed according to Siewert's standards. Results: According to Siewert classification, 7 had adenocarcinoma of the distal esophagus (Type Ⅰ), 134 had true carcinoma of cardia (Type Ⅱ ), and 75 had subcardial carcinoma (TypeⅢ ). The third type lesions 5-year survival rate was 71. 4％, 65. 7％ and 60. 0％ respectively, Type Ⅲ patients,without obvious differences for age and sex. were more in elderly 60-year-old, with more than men.Advanced stage patients increased obviously in type Ⅱ and type Ⅲ patients. The 3 type of patients with organizational credit tubular adenocarcinoma. Pathology grade, grade Ⅱ and Ⅲ were to see frequently. Three basic type of tumor lymph node metastasis rate was to equal. Conclusion : According to Siewert 's classification ,AEG is classified into type Ⅰ, type Ⅱ and type Ⅲ . Between type Ⅰ and type Ⅱ , differences are dominating,while between type Ⅱ and type Ⅲ tumors, similarities are more prominent. Further study is still necessary to clear the relations between them thoroughly.%目的:探讨食管胃交界腺癌Siewert分型的临床病理特征.方法:对216例食管胃交界腺癌病人的临床、病理及预后随访进行研究,利用Siewert分型方法进行分型.结果:按照 Siewert分型,此组病例食管远端腺癌7例(Ⅰ型),真性贲门癌134例(Ⅱ型),贲门下胃癌75例 (Ⅲ型).分型病例以Ⅱ型(62.1%)多见,而Ⅰ型(3.2%)少见;三型病变5年生存率分别为71.4%、65.7%和60.0%;三型患者在年龄、性别方面无明显差异,均多见于60岁左右老年人,以男性多见.Ⅱ、Ⅲ型晚期病人明显增多;三型病人组织学分型均以管状腺癌最常见,病理学分级Ⅰ级少见,Ⅱ和Ⅲ级常见;三型肿瘤淋巴结转移率基本相当.结论:食管胃交界腺癌按照Siewert分型分为三型,以Ⅱ和Ⅲ型多见,Ⅰ型少见,Ⅱ型和Ⅲ型病人基本情况相似,与Ⅰ型间存在差异.
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