胸腔积液中纤维连接蛋白、层连蛋白、Ⅳ型胶原与胸膜纤维化的相关性

摘要

Objective:To investigate the pleural effusion in fibronectin laminin type Ⅳ collagenand pleural fibrosis .Methods:Using the enzyme immunoassay test in 40 cases of tuberculous exudate and transudate in 40 cases of fibronectin laminin collagen type Ⅳlevel .Results :the tuberculous pleural effusion in fibronectin ,laminin ,collagen type Ⅳ levels were higher than those of transudate(P<0 .05) .Conclusion :fibronectin laminin collagen type Ⅳlevel in pleural fibrosis formation plays an important role in the process .%目的：探讨胸腔积液中纤维连接蛋白（FN ）、层连蛋白（LN ）、Ⅳ型胶原（ColⅣ）与胸膜纤维化的关系。方法：采用酶联免疫检测仪检测40例结核性渗出液及40例漏出液中的F N、L N、ColⅣ的水平。结果：结核性胸腔积液中FN、LN、ColⅣ水平均高于漏出液（P＜0．05）。结论：FN、LN、ColⅣ在胸膜纤维化的形成过程中起重要作用。