目的：观察高同型半胱氨酸（Hcy ）血症伴发急性脑梗死患者周围神经传导速度的改变。方法：选取住院的患者和门诊体检者90例，分为高H cy血症合并急性脑梗死组30例、高 H cy血症组30例、健康对照组30例，采用神经肌电诱发电位仪测定上下肢神经传导速度，对患者周围神经的传导速度进行比较分析。结果：与健康对照组相比，高 H cy血症合并急性脑梗死组、高 H cy血症组的神经传导速度均减慢，差异有统计学意义，高 H cy血症合并急性脑梗死者神经传导速度更慢，差异有统计学意义。结论：高H cy血症合并急性脑梗死患者周围神经神经传导速度减慢，可能与叶酸、维生素B12代谢异常及动脉粥样硬化导致神经营养障碍有关。%Objective:To observe the peripheral nerve conduction velocity in acute cerebral infarction pa‐tients with hyperhomocysteinemia .Methods :A total of 30 patients reviewed in this study ,who were admitted into the department of neurology in the first hospital of YuLin ,were equally divided into the control group ,hyperhomo‐cysteinemia acute cerebral infarction without group and hyperhomocysteinemia with acute cerebral infarction group . Electrophysiologic studies and the peripheral nerve conduction velocity were detected and carefully analyzed .Re‐sults :Compared with the control , the peripheral nerve conduction velocity of patients in hyperhomocysteinemia group and cerebral vascular disease combined with hyperhomocysteinemia group were significantly slower .And cere‐bral vascular disease combined with hyperhomocysteinemia group was slower .Conclusions :The slowing of peripher‐alnerve conduction velocity in acute cerebral infarction patients with hyperhomocysteinemia is related to neural nutri‐tion disorders because of the metabolic abnormalities in folic acid ,vitamin B12 and atherosclerosis .
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