首页> 中文期刊>陕西中医 >黄芪竹叶汤治疗消渴病气阴两虚证及对改善胰岛β细胞功能和胰岛素抵抗的作用研究

黄芪竹叶汤治疗消渴病气阴两虚证及对改善胰岛β细胞功能和胰岛素抵抗的作用研究

     

摘要

目的:分析消渴病气阴两虚证治疗中黄芪竹叶汤对胰岛β细胞功能及胰岛素抵抗的作用。方法:应用随机数字表法,将80例消渴病气阴两虚症患者分为两组,每组40例。对照组接受西药治疗,治疗组接受在西药联合黄芪竹叶汤治疗。分析两组治疗前后胰岛β细胞功能及胰岛素抵抗情况。结果:在完成8周治疗后,治疗组 FINS 、2hINS 、空腹 C 肽、2hC 肽及HOMA-β高于对照组,HOMA-IR 低于对照组(P<0.05)。治疗期间两组间不良反应发生率比较,差异无统计学意义(P>0.05)。结论:在消渴病气阴两虚症的治疗中黄芪竹叶汤可有效的改善患者的胰岛β细胞功能及胰岛素抵抗情况。%Objective :To analyze the islet β-cell function and insulin resistance of Huangqi Zhuye decoction in diabetes syndrome of deficiency of both qi and yin .Methods :Application of random number table method ,80 patients of diabetes syndrome of deficiency of both qi and yin were divided into two groups ,40 in each group .Control group treated with western medicine ,treatment group treated with western medicine combined Huangqi Zhuye decoction .Analysis the islet β cell function and insulin resistance of the two groups .Results :After 8-week treatment ,the treatment group FINS , 2 hINS ,fasting C peptide ,2h C peptide and HOMA-β was higher than control group ,the HOMA-IR was lower than con-trol group(P< 0 .05) .There was no statistically significant difference of incidence reactions between the two groups dur -ing treatment(P> 0 .05) .Conclusion :The treatment of Huangqi Zhuye decoction can effectively improve the islet β cell function and insulin resistance of diabetes syndrome of deficiency of both qi and yin .

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