食品中农药残留的累积性暴露评估方法研究

摘要

The potential cumulative effect of pesticide residues has been drawn more and more attention by many national governments and consumers. A lot of research work on assessments of cumulative exposure to pesticide residues which have a common mechanism such as organophosphate and carbamate has been done by US,The Netherlands,Brazil,Denmark and other countries. The main assessment methods of cumulative exposure such as Hazard Index, Cumulative Risk Index, Reference Point Index, Margin of Exposure, Toxicity Equivalence Factors were reviewed ,and the influence of uncertain factors were analyzed.%食品中农药残留潜在的累积效应已受到许多国家政府部门以及消费者越来越多的关注.美国、荷兰、巴西、丹麦等国家都已分别对具有共同作用机制的有机磷类和氨基甲酸酯类农药残留的累积性暴露评估做了大量的研究工作.本文对危险指数(HI)、累积风险指数(CRI)、参考点指数(RPI)、暴露边界(MOE)以及毒性当量因子(TEF)等国外目前研究累积性暴露评估的主要方法进行了综述,并对不确定因素的影响进行了分析.