腹针联合二甲双胍治疗肥胖型多囊卵巢综合征患者的临床研究

摘要

目的：观察针刺结合二甲双胍治疗肥胖型多囊卵巢综合征（polycystic ovary syndrome ，P‐COS）的临床疗效。方法将18～36岁肥胖型 PCOS患者42例随机分为腹针组、二甲双胍组及腹针联合二甲双胍组，每组各14例。3组连续治疗6个月后，在月经周期第3～5天或闭经者经B超检查未见优势卵泡时，检查血性激素（LH、FSH、LH／FSH）水平、BMI指数及腰腹围指标。结果治疗后，3组性激素水平、BMI指数及腰腹围指标均较治疗前明显改善（P＜0.05）；组间比较，腹针组和二甲双胍组性激素水平、BMI指数及腰腹围指标差异均无统计学意义（P＞0.05），但腹针联合二甲双胍组上述指标的改善效果明显优于腹针组和二甲双胍组（P＜0.05）。结论针刺配合二甲双胍治疗肥胖型 PCOS 优于单独采用针刺治疗或单用二甲双胍治疗。%Objective To observe the clinical effect of abdominal acupuncture combined with metformin in treating obese polycystic ovary syndrome(PCOS).Methods Obese PCOS patients with age between 18~36 were divided into abdominal acupuncture group ,metformin group and integrated (abdominal acupuncture combined with metformin)group randomly ,with 14 cases in each group. All patients were treated for half a year.Serum level of sex hormones ,body mass index(BMI)and abdomen circumference(AC)were observed and compared among three groups.Results After treatment ,the weight ,AC ,BMI and sex hormones of three groups were all improved obvi‐ously(P<0.05). The weight ,AC ,BMI and sex hormones of integrated group improved more obviously than ab‐dominal acupuncture group and metformin group (P< 0.05) ,and there was no significant difference between ab‐dominal acupuncture group and metformin group.Conclusion The treatment of abdominal acupuncture combined with metformin is superior to the treatment of abdominal acupuncture or metformin only.