人乳头状瘤病毒、单纯疱疹病毒2型和巨细胞病毒感染与宫颈癌的相关性研究进展

摘要

宫颈癌是最常见的女性生殖道恶性肿瘤,人乳头状瘤病毒感染(HPV)是宫颈癌的主要致癌因素,此外其他病毒感染如单纯疱疹病毒2型( HSV-2)人类巨细胞病毒(HCMV)也引起了人们的重视.作者对HPV HSV-2 HCMV的感染途径,感染的人群,致癌机制与宫颈癌之间的相关性研究进展作一综述.%Cervical cancer (CC) is an important public health problem worldwide. HPV are the primary etiologic agents of cervical cancer. However, HPV can not be found in every patient with the disease and other factors have been associated with cervical cancer. In recent years, studies have revealed that other sexually transmitted factors such as HSV-2, HCMV may be cofactors in the malignancy of cervical uterus, In this review, research progress were summarized on the infection way and infected people of HPV, HSV-2 and HCMV, as well as the relationship between their mechanism and cervical cancer.