阿托伐他汀对急性心肌梗死患者血脂及超敏C反应蛋白的影响

摘要

Objective To observe the effect of atorvastatin on blood lipid and high-sensitivity C-reactive protein in patients with acute myocardial infarction.Methods 90 acute myocardial infarction patients in our hospital were selected from September 2011 to September 2012.All the patients were divided into study group and control group randomly,45 cases in each group.The patients in control group were given conventional drug treatment.The patients in study group were given atorvastatin.The changes of the heart function levels,blood lipid levels and high-sensitivity C-reactive protein of the two groups 1 week after treatment were compared.Results After treatment,the heart function levels and hs-CRP of the two groups were improved significantly (P ＜ 0.05).The blood lipid levels of study group were improved more significantly than those of control group (P ＜ 0.05).Compared with the control group,the IVST and the LVDD of the study group reduced significantly,LVEF was improved significantly,TG,LDL,TC decreased significandy,hs-CRP were lower significantly(P ＜ 0.05).Conclusion Atorvastatin can effectively improve the level of cardiac function,blood lipid levels and hs-CRP content in patients with acute myocardial infarction.It is worthy of further promotion of clinical application.%目的 探讨阿托伐他汀对急性心肌梗死患者血脂及超敏C反应蛋白的影响.方法 选取2011年9月至2012年9月我院收治的急性心肌梗死患者90例,随机分为研究组和对照组,每组45例.对照组入院后给予常规药物进行治疗,研究组在此基础上给予阿托伐他汀.比较两组患者入院时和治疗1周后心功能水平、血脂水平及超敏C反应蛋白(hs-CRP)含量的变化.结果 与治疗前相比,两组患者治疗后IVST、LVDD、LVEF等心功能水平及hs-CRP水平均明显改善,研究组TG、LDL、TC等血脂水平与治疗前比较均有所改善,差异具有统计学意义(P＜0.05).与对照组相比,研究组治疗后IVST和LVDD明显降低,LVEF明显提高;TG、LDL、TC水平均明显降低；hs-CRP水平明显降低,两组上述指标比较,差异均具有统计学意义(P＜0.05).结论 阿托伐他汀能够明显改善急性心肌梗死患者的心功能水平、血脂水平以及hs-CRP水平.