前列地尔联合生长抑素治疗重症急性胰腺炎的临床观察

摘要

目的 观察前列地尔联合生长抑素治疗重症急性胰腺炎的临床疗效.方法 将68例重症急性胰腺炎患者随机分为生长抑素治疗组(对照组,32例)和前列地尔+生长抑素治疗组(观察组,36例).比较两组患者症状、腹部体征消失时间、血淀粉酶恢复正常的时间.结果 观察组、对照组的有效率分别为94.44 %、65.63 %.两组疗效比较差异有统计学意义,P<0.05.结论 前列地尔联合生长抑素治疗重症急性胰腺炎安全有效.%Objective To investigate the effect of alprostadil combined with somatostatin on severe acute pancreatitis. Methods 68 patients with severe acute pancreatitis were divided into 2 groups: control group ( 32 cases )was treated with somatostatin; treatment group ( 36 cases )was treated with alprostadil combined with somatostatin. The symptoms, signs, AMS in serum of the two groups were observed and compared. Results The effective rates of treatment group and control group were 94. 44 % and 65. 63 % respectively, there was obvious difference between the two groups( P < 0. 05 ). Conclusion Alprostadil combined with somatostatin is safe and effective to treat severe acute pancreatitis.