替加环素致铜绿假单胞菌二重感染五例

摘要

目的：研究替加环素的使用与铜绿假单胞菌二重感染之间的关系。方法对我院2013年1-5月住院期间应用替加环素的患者进行回顾性研究。对患者年龄、基础疾病、原发感染灶、预后、细菌培养结果、所用抗菌药物种类及应用替加环素后出现铜绿假单胞菌二重感染的部位和类型及替加环素用药天数等进行统计分析。结果12例患者出现铜绿假单胞菌二重感染5例(41．7%)；应用替加环素后至铜绿假单胞菌检出的时间平均为20 d。结论在应用替加环素的过程中需警惕有无铜绿假单胞菌二重感染的出现。%Objective To investigate the risk factors of superinfection caused by tigecycline. Methods The clinical data such as age,original disease,time of hospitaIization,antibiotics used and the kinds of superinfection caused in 12 cases were analyzed. Results There were 5(41. 7%) cases with superinfection by pseudomonas aeruginosa from 12 hospitalized patients. Conclusion Patients with treatment of tigecycline are predisposed to superinfection with pseudomonas aeruginosa.