首页> 中文期刊> 《实用心脑肺血管病杂志 》 >国产与进口药物洗脱支架在冠状动脉支架置入术中应用效果-费用的对比研究

国产与进口药物洗脱支架在冠状动脉支架置入术中应用效果-费用的对比研究

摘要

Objective To compare the application effect and cost in intracoronary stent implantation between domestic and imported drug eluting stent.Methods A total of 791 coronary heart disease patients undergoing intracoronary stent implantation were selected in a Grade 3 and first-class hospital in 2013,and they were divided into A group (using domestic drug eluting stent,n =398) and B group (using imported drug eluting stent,n =393) according to the types of stents.During the intracoronary stent implantation,patients of A group used Shanghai Minimally-invasive Firebird Ⅱ Drug-eluting Stents,while patients of B group received United States Medtronic Endenvor Drug Eluting Stents.Clinical data,operative success rate,locations of coronary artery lesions,number of implanted stents,clinical outcome,hospitalization related expenses and incidence of complications were compared between the two groups.Results Patients of the two groups completed the operation successfully,the operative success rates of the two groups were both 100.0%.No statistically significant differences of proportion patients with left main coronary artery lesions,with anterior descending branch lesions,with circumflex branch lesions,with posterior descending branch lesions,with obtusemarginal branch lesions,with diagonal branch lesions,with right coronary artery lesions,or number of implanted stents was found between the two groups (P > 0.05).No statistically significant differences of improvement rate was found between the two groups (P > 0.05).No statistically significant differences of examination expense,inspection expense or operation expense was found between the two groups (P > 0.05);ward bed expense,material expense and total hospitalization related expenses of B group were statistically significantly more than those of A group,durg casts of B group was statistically significantly lower than that of A group (P < 0.05).No one of the two groups occurred recurrent angina pectoris,acute occlusion or acute thrombosis during hospitalization.Conclusion Domestic and imported drug eluting stent have similar application effect on intracoronary stent implantation,but using domestic drug eluting stent can significantly reduce the medical expenses.%目的 比较国产与进口药物洗脱支架在冠状动脉支架置入术中的应用效果及费用.方法 选取2013年在哈尔滨某三甲医院行冠状动脉支架置入术的冠心病患者791例,根据支架类型分为使用国产药物洗脱支架者398例(A组)和使用进口药物洗脱支架者393例(B组).A组患者置入上海微创FirebirdⅡ药物洗脱支架,B组患者置入美国美敦力Endenvor药物洗脱支架.回顾性分析两组患者的病历资料,比较两组患者手术成功率、冠状动脉病变部位、置入支架数量、临床转归、住院相关费用及并发症发生情况.结果 两组患者均顺利完成手术,手术成功率均为100.0%.两组患者左主干、前降支、回旋支、后降支、钝缘支、对角支、右冠状动脉病变者所占比例及置入支架数量比较,差异均无统计学意义(P>0.05).两组患者好转率比较,差异无统计学意义(P>0.05).两组患者检查费用、检验费用及手术费用比较,差异无统计学意义(P>0.05);B组患者床位费用、材料费用及住院总费用均高于A组,药物费用低于A组(P<0.05).住院期间两组患者均未出现再发心绞痛、急性闭塞、急性血栓形成等.结论 国产与进口药物洗脱支架在冠状动脉支架置入术中的应用效果相当,但国产药物洗脱支架可降低患者的医疗费用.

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