多层螺旋 CT灌注成像在肺癌病理分型中的应用

摘要

Objective To investigate the characteristics of different pathological tissues of lung cancer in multilayer coi -ling CT Perfusion imaging .Methods Multilayer coiling CT perfusion imaging data of 30 cases of lung cancer in different patho-logical types were retrospectively analyzed and compared .Results The PER,PE,TTP and BV rates between adenocarcinoma and squamous carcinoma had no statistically significant difference (P>0.05).With the reducing of lung cancer differentiation degree , thePER,PE and BV rates gradually decreased ,the difference was statistically significant ( P<0.05);With the reduc-ing of lung cancer differentiation degree,TTP increased gradually,but the difference wasn’t significant(P>0.05).There were 3 cases of squamous cell carcinomas with typeⅠTDC curve,and 10 cases with typeⅡTDC curve;and there were 13 cases of adenocarcino-ma with typeⅠTDC curve,4 cases with typeⅡTDC curve,the difference was statistically significant (P<0.05).Conclusion Multilayercoiling CT perfusion imaging can reflect the differentiation of different histopathologic types of lung cancer ,and provide important information for clinical treatment .%目的：探讨不同病理组织类型肺癌多层螺旋CT灌注成像的特点。方法回顾性分析30例不同病理类型肺癌患者多层螺旋CT灌注成像资料，并加以分析比较。结果腺癌及鳞癌患者PER、PE、TTP及BV值比较，差异均无统计学意义（P＞0．05）。随着肺癌分化程度减低，PER、PE和BV值逐渐降低，差异有统计学意义（P＜0．05）；随着肺癌分化程度减低，TTP值逐渐增高，但差异无统计学意义（ P＞0．05）。鳞癌Ⅰ型TDC曲线3例，Ⅱ型10例；腺癌Ⅰ型13例，Ⅱ型4例，差异有统计学意义（P＜0．05）。结论多层螺旋CT灌注成像能反映不同病理组织类型肺癌的分化程度，可为临床治疗提供重要信息。