钼靶 X线对乳腺癌的临床诊断价值及其与乳腺癌病理相关性的研究

摘要

目的：评估钼靶X线对浸润性导管乳腺癌的诊断价值及与其临床病理特征关系。方法回顾性分析231例乳腺癌患者的临床资料。采用Fisher精确检验，χ2检验，Spearman相关回归分析钼靶X线与乳腺癌临床病理特征的关系。结果231例患者接受乳房X线检查，恶性钙化在人表皮生长因子受体2（HER2）阳性患者（P＝0．001）或肿瘤直径＞2 cm的乳腺癌患者中最常见（P＝0．006）。钼靶X线多形型与p53阳性状态（P＝0．039）及淋巴结转移（P＝0．048）相关，而钼靶X线模糊非晶型与HER2受体阳性状态（P＝0．026）相关。高表达Ki-67的肿瘤患者常见明显的肿块（P＝0．002）。结论 X线特征与乳腺癌临床病理特征相关，相关性反映肿瘤的属性，并且可指导临床治疗。%Objective To evaluate the clinical value of X-ray mammography in the diagnosis of breast cancer and its correlation with clinicopathological features.Methods A retrospective analysis of clinical data of 231 cases of breast cancer were conducted.Fisher's exact test,χ2 test,Spearman regression analysis were used to detect the relationship between X-ray mammogra-phy and clinicopathological features of breast cancer.Results 231 patients received breast X-rays,malignant calcification was common in the human epidermal growth factor receptor 2 (HER2)-positive patients (P=0.001) or breast cancer patients with tumor diameter>2 cm (P=0.006).X-ray mammography pleomorphic type and p53-positive status (P=0.039) and lymph node metastasis (P=0.048) were correlated,while molybdenum target X-ray amorphous and vague HER2 receptor-positive status (P=0.026) were correlated.Patients with high expression of Ki-67 have common tumor mass (P=0.002).Conclusion X-ray features are associated with clinicopathological features of breast cancer,which reflect tumor properties,it can guide clinical treat-ment.