首页> 中文期刊> 《大众科技》 >独活寄生汤联合来氟米特治疗类风湿关节炎临床研究

独活寄生汤联合来氟米特治疗类风湿关节炎临床研究

             

摘要

Objective: to live with parasitic soup from the joint special piece of clinical curative effect of observation for the treatment of rheumatoid arthritis. Methods: the unique living parasitic soup from the joint piece for the treatment of rheumatoid arthritis (liver and kidney deficiency type) clinical efficacy was retrospectively analyzed. Application of random Numbers table put into 120 patients were randomly divided into treatment group and control group, two groups of 60 cases, control group given to fluorine milt treatment; Treatment group shall be the sole living parasitic soup from the joint special treatment, as a course for 6 months, respectively, before treatment, treatment of 1 month, 2 months, 3 months for patients with DAS-28 marking and HAQ health assessment questionnaire is adopted to improve the quality of life assessment. Results: the total effective rate in treatment group, and show the efficiency of 88.33% and 80%, respectively; the control group total effective rate, efficiency of 73.33% and 61.61% respectively. The total effective rate, the efficiency of the treatment group was significantly better than the control group. Two groups of patients with HAQ scores, DAS-28 grading is improved in the treatment of 1 month, in remission. Two groups of patients with HAQ scores, DAS-28 score after 2 months continue to decrease, preliminary alleviate illness, before this treatment had significant difference (P < 0.05), compared between groups still there was no significant difference (P > 0.05);Two groups at the end of the treatment of patients with HAQ scores, DAS-28 score decreased significantly, the control condition, the group before and 1 month treatment had significant difference (P < 0.05), compared between groups had significant difference (P < 0.05).Conclusion: unique live parasitic soup from joint piece can effectively improve the liver and kidney deficiency type of rheumatoid arthritis patients clinical symptoms and laboratory indexes, and no obvious adverse reaction, improve the quality of survival, satisfactory results have been achieved.%目的:对独活寄生汤联合来氟米特片治疗类风湿关节炎的临床疗效进行观察。方法:对独活寄生汤联合来氟米特片治疗类风湿关节炎(肝肾亏虚型)的临床疗效进行回顾性分析;应用随机数字表把纳入的120例患者随机分为治疗组和对照组,两组各60例,对照组给予来氟米特片治疗;治疗组予以独活寄生汤联合来氟米特片治疗,1疗程为6个月,分别于治疗前、治疗1个月、2个月、3个月对患者进行DAS-28评分并采用HAQ健康评估问卷进行生存质量评估。结果:治疗组总有效率、显效率分别为88.33%和80%;对照组总有效率、显效率分别为73.33%和61.61%。总有效率、显效率治疗组均显著优于对照组。两组患者HAQ评分、DAS-28评分在治疗1个月均有所改善,病情得到控制;两组患者HAQ评分、DAS-28评分在2个月后仍继续减少,病情初步缓解,较本组治疗前有显著性差异(P<0.05),组间相比仍无显著性差异(P>0.05);两组患者在治疗结束时HAQ评分、DAS-28评分明显减少,病情完全控制,较本组治疗前及治疗1个月有显著性差异(P<0.05),组间相比均有显著性差异(P<0.05)。结论:独活寄生汤联合来氟米特片可有效改善肝肾亏虚型型类风湿关节炎患者的临床症状及实验室指标,且无明显不良反应,提高生存质量,取得了满意效果。

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