16％阿维·毒死蜱微囊悬浮剂的制备及其缓释性能研究

摘要

以聚脲为囊壁材料,采用界面聚合法制备了阿维菌素·毒死蜱微囊悬浮剂,并对样品进行了缓释性能的测定.结果表明,采用0203为乳化剂、D-305为分散剂可制得囊型良好、平均粒径为2.967 μm,包封率、悬浮率均在95％以上,贮存性能稳定的微囊悬浮剂.释放性能测定表明,该微囊悬浮剂2种成分的释放规律均符合一级动力学方程,分别为Q(阿维)=63.538 26(1-e-0.12071t) (R2 =0.987 5),Q(毒死蜱)=70.956 28(1-e-0.146 76t)(R2 =0.985 3),阿维菌素、毒死蜱在60d时的累积释放率分别为67.4％、73.7％,说明该微囊悬浮剂具有良好的缓释性能.%Microcapsule suspension (CS) formulation containing abamectin and chlorpyrifos was first prepared via interface polymerization method using polyuria as wall material.The released behavior of the product was also studied in order to evaluate the performance.The results showed that the microcapsule with the average particle size of 2.967μm and both the encapsulation ratio and suspension ratio of above 95 ％ could be obtained using 4,4'-methylenedi and diethylenetrimine as wall material,emulsifier 0203,and D-305 as dispersing agent.The microcapsules showed satisfied surface morphology and good storage stability.The research on release behavior showed that both the two active ingredient' s release curves were consistent with First-level reaction with equation ofQ (abamectin) =63.538 26 (1-e-0.12071t) (R2 =0.987 5) and Q (chlorpyrifos) =70.956 28 (1-e-0.14676t) (R2 =0.985 3).The release rates of abamectin and chlorpyrifos were 67.4％ and 73.7％ after 60 days respectively.Abamectin + chlorpyrifos CS displayed good controlled-release characteristics and satisfied the necessary prerequisites for prolonged control period.