目的 探讨腹腔镜(LPS)与开腹手术(LPT)在早期卵巢癌全面分期手术中的应用价值.方法 回顾性分析接受手术治疗的150例早期卵巢癌患者的临床资料,根据手术方式不同将患者分为LPS组和LPT组,每组各75例.观察两组患者的手术一般情况,并对两组患者的手术效果、术后恢复情况、肿瘤标志物水平和1年生存率进行比较.结果 LPS组患者的手术时间、术后住院时间均明显短于LPT组(P﹤0.001),术中出血量明显少于LPT组(P﹤0.001);LPS组患者的腹主动脉旁淋巴结切除数、盆腔淋巴结切除数均明显多于LPT组(P﹤0.001);LPS组患者术后胃肠功能恢复时间明显短于LPT组(P﹤0.001),但两组患者术后并发症发生率比较,差异无统计学意义(P﹥0.05);LPS组患者手术前后HE4、CA125水平差值均明显高于LPT组(P﹤0.001);两组患者的1年生存率比较,差异无统计学意义(P﹥0.05).结论 LPS在早期卵巢癌全面分期手术中有较好的应用价值,可促进患者术后康复,具有良好的临床应用价值.%Objective To investigate the value of laparoscopic (LPS) and laparotomy (LPT) in the treatment of early-stage ovarian cancer. Method The clinical data of 150 patients with early-stage ovarian cancer were retrospectively ana-lyzed. Patients were grouped as LPS group and LPT group as per respective surgeries delivered, with 75 patients in each. The general conditions, surgery effect, postoperative recovery, tumor markers and 1-year survival rate of the two groups were observed and compared. Result The operative time and postoperative hospital stay of LPS group were shorter than those of LPT group (P<0.001), and so did the intraoperative blood loss (P<0.001);In the LPS group, there were more pa-ra-aortic lymph nodes and pelvic lymph nodes were resected than LPT group (P<0.001);LPS group had faster recovery of postoperative gastrointestinal function than the LPT group (P<0.001), while the incidence of postoperative complica-tions were similar in both groups (P>0.05); the difference of HE4 and CA125 levels before and after surgery in LPS group was greater than that in LPT group (P<0.001);and the 1-year survival rates were also comparable in the two groups (P>0.05). Conclusion LPS is effectively applicable in comprehensive surgical staging for early-stage ovarian cancer, it can promote postoperative recovery, and is clinically beneficial.
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