目的 调查3所三级甲等医院清洁手术预防使用抗菌药物的情况,评价其应用的合理性.方法 抽取3所医院2011年9月清洁手术(甲状腺、乳腺、腹股沟疝、肾脏、颅脑手术)病例各50份,冠状动脉造影病例各20份,对病例是否使用抗菌药物、抗菌药物的品种、给药时机、给药时限及抗菌药物联合使用情况等进行统计分析.结果 清洁手术及冠状动脉造影诊断预防使用抗菌药物3所医院合计总体使用比例分别为67.3%和57.25%,品种选择合格率为60.8%,用药时机合格率为83.3%,使用疗程合格率为37.5%.结论 3所医院清洁手术预防使用抗菌药物,仅给药时机情况较好,抗菌药物的使用率、品种的选择及使用疗程都存在一定的不合理性.%Objective To investigate on the preventive use of antibiotics of three grade A class 3 hospitals,and to evaluate the rationality of the usage. Methods 50 cases of aseptic operations (thyroid,breast,inguinal hernia,kidney and brain operations) in September of 2011 of the three hospitals and 20 cases of coronary angiography were analyzed in the aspect of utilization,kinds,administration time, time of therapy and the combined use frequency of antibiotics. Results The frequency of preventive using antibiotics was 67. 3 % and 57. 25 % , respectively in the aseptic operation and coronary angiography. The reasonable chosen rate of kinds was 60. 8%, the reasonable chosen rate of administration time was 83. 3% ,and the reasonable chosen rate of time of therapy was 37. 5%. Conclusions The utilization frequency, chosen of kinds and time of therapy of antibiotics are not as reasonable as requested except the administration time of antibiotics in these three grade A class 3 hospitals.
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