Objective:To study the efficacy of ultrasound and water capsule-guided local injection of botulinum toxin type A (BTX-A) treatment on patients with facial spasm. Methods: Ninety-six cases of facial spasm were randomly divided into oral drug treatment group (A group) (48 cases) and ultrasound and water capsule-guided local injection of botulinum toxin type A treatment group (B group) (48 cases). Cohen, Acbert spasms strength grade scores in each cases with facial spasm were recorded. Therapeutic effect, duration, significant efficiency and muscle spasms strength were compared before and 6 months after treatment. Results:The muscle spasms strength showed no significant change in A group after the treatment. However, the muscle spasms strength was decreased significantly in B group after treatment (P展开▼