injectable botulinum toxin formulations and processes of long-term use of the therapeutic or cosmetic effect

摘要

The present invention relates to novel injectable compositions comprising botulinum toxin which may be administered to an individual for various therapeutic, aesthetic and / or cosmetic purposes. Injectable compositions encompassed by the invention have one or more advantages over conventional botulinum toxin formulations, including reduced antigenicity, reduced tendency to have undesirable localized diffusion after injection, longer duration of clinical efficiency or increased relative potency, faster onset of efficacy. clinical condition and / or improved stability. According to the invention, a single treatment of the injection compositions provides significant clinical responses and at least a duration of effect of 6 months in an individual undergoing treatment as offered by the treatment procedures described.