舒芬太尼复合丙泊酚对高血压脑出血手术患者麻醉效果分析

摘要

目的：探讨舒芬太尼复合丙泊酚对高血压脑出血手术患者的麻醉效果。方法：选取高血压脑出血手术患者144例，随机分为观察组和对照组各72例，对照组给予芬太尼麻醉诱导，术中以芬太尼和丙泊酚维持；观察组给予舒芬太尼麻醉诱导，术中以舒芬太尼和丙泊酚维持。分别以麻醉诱导前和麻醉诱导后3 min、插管后0 min 和5 min、切皮、开骨瓣、缝硬脑膜、手术结束后0 min 和30 min 时为 T0~T8，记录血压。统计2组高血压、低血压、心动过速和过缓、呼吸抑制以及术后呛咳的发生率。结果：T2~T8时观察组的收缩压和舒张压均明显低于对照组，差异有统计学意义（P＜0.05）。观察组的高血压、心动过速、呼吸抑制及术后呛咳发生率均明显低于对照组，差异有统计学意义（P＜0.05）。结论：与芬太尼相比，舒芬太尼复合丙泊酚应用于高血压脑出血颅内血肿清除患者围手术期可有效稳定术中血压，减少不良反应发生。%Objective:To investigate the anesthesia efficacy of sufentanil combined with propofol on the patients with hypertensive cerebral hemorrhage operation. Methods: One hundred and forty-four cases with hypertensive cerebral hemorrhage operation were randomly divided into the observation group and control group, with 72 cases in each group. The control group was given fentanyl anesthesia induction, and fentanyl and propofol intraoperative maintenance. The observation group was given sufentanil anesthesia induction, and sufentanil and propofol intraop-erative maintenance. Before anesthesia induction was T0, after anesthesia induction for 3 min was T1, after intuba-tion for 0 min was T2, after intubation for 5 min was T3, cut the skin was T4, open bone flap was T5, sew the dura mater was T6, after surgery for 0 min was T7, after surgery for 3 min was T8. The blood pressure was recorded at T0~T8. The hypertension, hypotension, tachycardia, the slow, respiratory depression and postoperative choking cough incidence of two groups were recorded. Results: The systolic blood pressure and diastolic blood pressure of the patients in the observation group in T2~T8 were obviously lower than those in the control group (P<0.05). The incidence of hypertension, tachycardia, respiratory depression and postoperative choking cough in the observation group after surgery were lower than those in the control group (P<0.05). Conclusion: Compared with fentanyl, sufentanil combined with propofol for the patients in hypertensive intracerebral hemorrhage removal operation could make the intraoperative blood pressure effectively stable and reduce the adverse reaction.