Twelve compounds were isolated from Micromelum falcatum and purified by repeated column chromatography on silica,Sephadex LH-20 gel,and HPLC and structurally identified by spectral analysis. The compounds were identified as 5-formyl-6,7-dimethoxycoumarin (1) ,isoscoploletin-β-D-glucoside (2) ,6-(irarcs-l-buten-3-only)-7-methoxycouma-rin (3) ,isoscopoletin-(6-hydroxyl-7-methoxyl coumarin,isoscopoletin) (4) ,microfalcatin isovalerate (5) .micromelin (6),syringin ( 7), coniferin ( 8 ), Methyl 2-0^3-D-glucopyranosylbenzoate ( 9 ) , 2-hydroxy-5-methoxy-trans-cinnamic acid (10) ,3 ,5-dimethoxyl-4-hydroxyl benzaldehyde (11) and o-sec-butyl phenol (12). Compound 1 previously synthesized but first isolated as natural product,and the other compounds were isolated from this plant for the first time except 5 and 6.%从小芸木属植物大管茎皮部位共分离得到12个化合物,运用MS、1H NMR和13C NMR等波谱方法并结合文献对照分别鉴定为5-formyl-6,7-dimethoxycoumarin(1),isoscoploletin-β-D-glucoside(2),6-(trans-1-buten-3-only)-7-methoxycoumarin(3),6-羟基-7-甲氧基香豆素(4),microfalcatin isovalerate(5),小芸木宁(6),丁香苷(7),coniferin(8),methyl2-O-β-D-glucopyranosylbenzoate(9),2-hydroxy-5-methoxy-trans-cinnamic acid(10),3,5-二甲氧基-4-羟基苯甲醛(11)和邻仲丁基苯酚(12).其中化合物1为新的天然产物；除5和6外,其余化合物均首次从该植物中分离得到.
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