Objective To investigate the serum calcitonin and C-reactive protein level changes for patients with bacterial infection. Method 107 cases with bacterial infections and 104 cases of non-bacterial infectious diseases the same period were chosen and were respectively set as the observation group and the control group. The serum calcitonin levels and C-reactive protein levels for the two groups were detected. The test results were analyzed. Results The PCT average positive rate in the observation group was significantly higher than the control group. The CRP levels in the observation group were significantly higher. The above comparison between the two groups was significant, and with statistical significance(P<0.05). The CRP testing positive rate had little difference in the two groups, and there was not statistically significance(P>0.05). The CRP detection sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic rate were significantly lower than the PCT. The differences for the two checks comparison were obvious, and there was statistically significance(P<0.05). Conclusion It has good specificity by monitoring the patient's serum PCT levels in patients with bacterial infections, and has certain guidance for clinical diagnosis and treatment.% 目的探讨细菌感染性疾病患者血清降钙素和C反应蛋白水平变化情况.方法选取细菌感染性疾病患者107例及同期非细菌感染性疾病患者104例分别作为观察组和对照组.对两组患者血清降钙素水平和C反应蛋白水平进行检测并分析.结果观察组PCT平均水平以及检测阳性率明显均高于对照组；观察组CRP平均水平明显高于对照组.组间差异均有统计学意义(P<0.05).两组患者CRP检测阳性率差别不大,无统计学意义(P>0.05).CRP检测灵敏度、特异度、阳性预测值、阴性预测值以及诊断符合率均明显低于PCT,两种检查比较,差异有统计学意义(P<0.05).结论通过监测患者的血清PCT水平观察患者细菌感染情况,具有较好的特异性,对临床诊治有一定意义.
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