Objective To analyze the clinicopathologic characteristics of male breast cancer (MBC). Methods Col-lected and retrospectively analyzed the clinical data of 12 patients histopathologically confirmed MBC and received treatment from Jan 2010 to Apr 2014. Results The median age was 58 years (range 42~79 years). The main clinical symptom of all the patients was retroareolar mass (n=12). Histologically, eleven patients were invasive ductal carcinoma and one patient had mixed histology including invasive ductal and loblar carcinoma. Three patients were at stage Ⅱ, seven patients were at stage Ⅲ. And ten patients had positive lymph nodes. ER and PR positivity percentage was respectively 75.0% and 66.7%. Conclusion Pa-tients with male breast cancer were always diagnosed oldly and at advanced clinical stage and they also usually have high level of hormone receptors. Although they positively receive comprehensive treatment, the prognosis is poor.%目的：分析男性乳腺癌患者的临床特点。方法收集2010年1月～2014年4月经病理确诊、接受治疗、临床资料较完整的12例男性乳腺癌患者的临床资料，进行回顾性分析。结果12例患者发病年龄为42～79岁，中位年龄为58岁。主要的首发症状为乳腺肿块（n=12，100％）。组织学类型为浸润性导管癌（n=11，91.7％）和混合性癌（n=1，8.3％）。肿瘤临床分期主要为域期（25.0％，n=3）和Ⅲ期（58.3％，n=7）。多数患者发生淋巴结转移（83.3％，n=10）。激素受体检查，ER+（75.0％，n=9），PR+（66.7％，n=8）。结论男性乳腺癌患者的诊断年龄偏大，临床分期较晚，激素受体水平较高。尽管男性乳腺癌患者获得积极的综合性治疗，但预后较差。
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