新辅助化疗联合保乳手术在中晚期乳腺癌治疗中的应用

摘要

目的 研究新辅助化疗在中晚期乳腺癌保乳治疗中的应用价值.方法 对接受新辅助化疗的100例中晚期乳腺癌患者临床疗效及保乳治疗效果进行分析.结果 化疗总有效率为64%,分期降低率为53%,42%的患者在化疗后可实现保乳治疗,其中31例患者行保乳治疗,随访3年无局部复发.结论 中晚期乳腺癌新辅助化疗后行保乳手术是安全可行的,可显著提高患者生活质量.%Objective To study the value of pre-operative chemotherapy combined with breast conservation surgery for the treatment of middle-advanced breast cancer.Methods The clinical efficacy and outcomes of breast conservation therapy in 100 patients with middle-advanced breast cancer received pre-operative chemotherapy were analyzed.Restuls Total efficacy, stadge decrease rate and breast conservation rate were 64%, 53% and 42% respectively. 31 patients received breast conservation therapy and there was no recurrence in following 3 years.Conclusion Breast conservation therapy after pre-operative chemotherapy in patients with middle-advanced breast cancer is safe and it can significantly improve the life quality of patients.