重症急性胰腺炎患者早期危险因素分析以及对预后的影响

摘要

目的 探讨重症急性胰腺炎(SAP)患者早期危险因素以及对预后的影响,为临床救治提供参考资料.方法 选取64例SAP患者,根据患者的预后情况分为死亡组和生存组,分析其早期危险因素,其中单因素分析采用t检验,多因素分析采用Logistic回归分析.结果 单因素分析结果显示,两组患者的年龄、BMI、通便时间、空腹血糖、血清白蛋白、血钙、动脉血氧分压、心率及呼吸频率差异具有统计学意义(P<0.05);Logistic回归分析结果显示,年龄、BMI、血清白蛋白、动脉血氧分压、心率、血钙差异具有统计学意义(P<0.05),其中危险因素为年龄、BMI、心率,保护因素为血清白蛋白、动脉血氧分压.结论 年龄、BMI、心率均为SAP的危险因素,因此对于年龄大的、心率快的患者要重点监测,同时患者的血清白蛋白低、动脉血氧分压低时也要引起注意,可使用药物进行控制,提高患者的生存率.%Objective To analyze the early risk factors affecting the prognosis of the patients with severe acute pancreatitis in order to provide the appropriate reference for clinical practice. Methods Sixty four pa-tients with severe acute pancreatitis were divided into death group and survival group according to the progno-sis. One single factor analysis was performed using student′s t test, multivariate analysis using Logistic regres-sion analysis. Results Univariate analysis showed that the factors including age, BMI, purge time, fasting blood glucose, serum albumin, calcium, blood pressure, heart rate, and respiratory rate were statistically significant difference (P<0.05). Logistic regression analysis showed that age, BMI, serum albumin, blood pressure, heart rate, blood calcium were into the equation and the difference was statistically significant (P<0.05). The risk factors were age, BMI and heart rate, the protection factors were serum albumin and arterial oxygen. Conclu-sion Age, BMI and heart rate are risk factors for severe acute pancreatitis. Therefore, the elderly patient with rapid heart rate should be focused on monitoring, while the patients with lower serum albumin and low arterial oxygen pressure should be paid more attention.