芦丁在水溶液中的降解动力学研究

摘要

Objective:To investigate the degradation kinetic characteristics of rutin in aqueous solution under different pH and temperatures.Methods:The concentration change of rutin in aqueous solution was determined by HPLC under different pH and temperatures.Base on the chemical reaction kinetic,the parameters of degradation kinetics were calculated under different conditions.The activation energy and half-life were evaluated.Results:The results indicated that thermal degradation kinetic model of rutin in aqueous solution follows first-order degradation kinetic process.The half-life period(t0.5)was 57.75 h under pH 9 in aqueous solution,and the energy of activation (Ea) was 39.3 k J· mol-1.Conclusion:Rutin was more stable in acidic aqueous solution and low temperature condition.The degradation of rutin can be observed in strong alkali conditions.%目的:研究芦丁水溶液在不同的pH、温度、离子强度、初始浓度条件下降解反应的动力学特征.方法:采用高效液相色谱法考察不同条件下芦丁含量随时间的变化,利用化学反应动力学的方法计算芦丁在不同环境下的降解反应动力学参数,预测其半衰期(t1/2)和活化能.结果:芦丁在不同环境条件下的降解反应均遵循一级动力学规律,在pH =3环境中最为稳定,强酸碱性条件下较容易降解,pH=9时的室温条件下半衰期为57.75 h,活化能为39.3 kJ·mol-1,随着离子强度的增加降解速率也随之加快,但初始浓度对其降解影响不大.结论:芦丁在酸性水溶液中较为稳定,随着pH的增大降解速率逐渐加快,呈现pH和温度依赖型,提示芦丁的使用和保存适宜在低温偏酸性条件下,避免碱性环境和高温条件.