神经递质与睡眠觉醒及学习记忆的关系研究

摘要

睡眠是一个主动的神经调节的过程,与神经系统内部的结构和神经递质的作用密切相关.目前关于睡眠与觉醒的机制尚未完全明确,许多神经递质参与睡眠与觉醒周期的调节,神经递质对学习记忆能力也有不同的影响.现对乙酰胆碱、去甲肾上腺素、多巴胺、5-羟色胺、一氧化氮及组胺等几种神经递质对睡眠与觉醒的调节及对学习记忆的影响予以综述.%Sleep is an active neural regulation process, which is closely associated with the internal structure of nervous system and the role of neurotransmitters.At present, the mechanisms of sleep and awakeness remain unclear.It is discovered that many neurotransmitters are involved in the regulation of sleepawakeness cycle.Neurotransmitters also have various effects on learning and memory.This paper will review neurotransmitters,such as acetylcholine,norepinephrine,dopamine,serotonin,nitric oxide,and histamine regarding the adjustation of sleep and awakeneas and effects on learning and memory.