Objective To investigate fungal infection of blood culture samples from Xuanwu Hospital , to provide the basis for clinical diagnosis and rational drug use. Methods The distribution of department, strain type and susceptibility results of fungal infection from blood culture specimens during 2010-2011 were analyzed. Results There were 564 cases positive infections in 11,250 blood culture specimens,including 39 cases fungal infection( 0. 35% ). Parapsiiosis Candida infection was the most common strain( 41.0% ),followed by Candida albicans(35. 9% ). The total drug-sensitive rate of 39 fungal:5-fluorocytosine 100% ,amphotericin B 97.4% ,voriconazole 76. 9% ,fluconazole 74.4% ,itra-conazole 61.5% . Conclusion Parapsiiosis Candida and Candida albicans were the common strains, which are sensitive to 5-fluorocytosine( 100% )and amphotericin B( 97.4% ).%目的 分析血培养标本中真菌感染状况,为临床诊断及合理用药提供依据.方法 对本院2010 ~2011年血培养标本结果为真菌感染的资料进行回顾性分析.结果 送检的11 250例血培养标本中阳性感染标本564例,其中真菌感染标本39例(检出率为0.35%),多来自外科ICU(32株).真菌感染标本中近平滑假丝酵母菌感染标本最多(41.0%),其次是白假丝酵母菌(35.9%).39株真菌总体药物敏感率是氟胞嘧啶100%,两性霉素B 97.4%,伏立康唑76.9%,氟康唑74.4%,伊曲康唑61.5%.结论 血培养真菌检出以近平滑假丝酵母菌和白假丝酵母菌为主.真菌株对氟胞嘧啶100%敏感,对两性霉素B基本敏感.
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